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It has been studied in placebo-controlled trials with durations up to 8 years. In the CORE and STAR study the predicted rates were based on the Gail score.
RELEVANT TO EVISTA [CORE] TRIALS). In 1994, a double-blind randomized trial of raloxifene, a synthetic “selective” anti-estrogen (SERM), versus placebo
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There were 11 invasive breast cancers in 2557 women on the EVISTA arm compared to 38 in 2576 women on the placebo arm. The CORE trial
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This result confirms data reported in 2004 in a large study of raloxifene, the Continued Outcomes Relevant to Evista (or CORE Trial). Women
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In the CORE trial, however, researchers found that Evista increased the risk for developing venous thromboembolism—1.7%, compared with
1 Sep 2006 the 4-year Continuing Outcomes Relevant to Evista (CORE) trial (N . The beginning of the CORE trial did not coincide with the end of the
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They were participating in the Multiple Outcomes of Raloxifene Evaluation ( MORE) and Continuing Outcomes Relevant to Evista (CORE) trials.
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